In-vivo approaches developed at Cophy to test our own ideas on the computational role (e.g. setting of flexible and specific communication between two groups of neurons as illustrated on the central brain) and on the laminar profile of brain rhythms using high resolution neuroimaging (macroscale level). We use also in-silico approaches to further tackle these questions and relate them to behaviour using neural networks at the mesoscale level (i.e. based on neural mass models that emulate the summed activity over layers) and at a more microscale level (Spiking neural networks in which we can both record the activity of individual neurons and of population of neurons) . These networks can be traited to perform attention and prediction tasks similar to human agents