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Manel Merabet Zennadi

Postdoc, INSERM

manel.zennadi@inserm.fr

Minibio
My work focuses on the cognitive mechanisms underlying neuropsychopathological disorders (Eating disorders, depression...). I am particularly interested in monoamine systems, especially the serotonin system, and I use neuroimaging techniques to study them in greater detail.

Long biography

After obtaining a scientific baccalaureate, I enrolled at the Faculty of Medicine in Annaba (Algeria). Following seven years of theoretical and practical studies, I graduated as a general physician. My journey into scientific research began with a Master's degree in Health Engineering, specializing in medical imaging, signals, and systems (MISS) in Lyon (France). During my Master's program, I completed an internship at CERMEP (a living imaging platform in Bron), where I gained hands-on experience in stereotaxic surgery on rats to create models of multiple sclerosis. I also had the opportunity to observe and study demyelination plaques using 11.7 T MRI through an optimal control technique at CREATIS in Villeurbanne.

With this experience and my growing interest in research, I pursued a path in clinical research for my thesis, focusing on using my backgrounds to evaluate the role of morphological (MRI) and metabolic (PET) brain imaging in diagnostic and therapeutic phenotyping of eating disorders. I was able to carry out three main projects I) Creation of an MRI atlas of the pituitary gland II) Study of the structure and function of the pituitary gland in anorexia nervosa III) Study of the relationship between brain serotoninergic activity and the effectiveness of SSRIs in bulimia nervosa.

Given my past experiences, I naturally have a leaning towards studying physio-pathological/cognitive mechanisms, especially through brain imaging. Joining the copy team was a natural fit for me, as my professional ambitions align with those of the team, which provides a stimulating environment that nurtures my scientific curiosity on multiple levels.

Manel's publications